ERYTHEMA MIGRANS
14 RCTs, no meta-analysis
- 2 studies enrolled > 200 patients
- Amoxi 20d vs azithro 7d: lower cure rate and more relapses in azithro. (p=0,02)
- Cefurox.ax vs doxy 20d: as effective, more related adverse events in doxy. (p=0,041)
- 1 study interrupted after 19 patients analyzed: 5/9 failure in roxithro. vs 0/10 in peni V
- cefurox.ax=peni V azythro=doxy peniV=mino* amoxy+probenecid=doxy azithro=amoxi+probenecid=doxy* cefurox.ax=doxy azithro=peniV* ceftriax=peniV azithro=peniV