MIC based therapies : Why bother? 

SBIMC/BVIKM - NVMM - VIZ joint meeting -- Antwerp, November 7-8th, 2002

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Table of Contents

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Who \ What do we treat?

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Which dose is optimal for treatment?

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MIC

Pharmacokinetics

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% Target Attainment at which %T>MIC is reached for BAL5788

Now, what about Resistance?

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Thus, suboptimal concentrations have the highest probability of inducing/selecting resistance

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Conclusions (1)

Cumulative Fraction of Response

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Conclusions (2)

And Finally….

We do NOT treat:

Author: J.W. Mouton

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