Median Days To Alleviation Of Symptoms (Phase III Studies) Influenza-Positive

Study Placebo Zanamivir Difference (95% CI)

10 mg IH b.i.d. (days) P value

SH 97 n = 160 n = 161 (0.5, 2.5)

6.0 4.5 1.5 0.004

A 97-98 n = 257 n = 312 (0.0, 1.5)

6.0 5.0 1.0 0.078

E 97-98 n = 141 n = 136 (1.0, 4.0)

7.5 5.0 2.5 < 0.001

Combined n = 558 n = 609 (1.0, 2.0)

6.5 5.0 1.5 < 0.001

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